Summary of Awards to Date

Chill and osmotic tolerance of Listeria monocytogenes.

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Date

Oct. 1, 2007 - Sep. 30, 2012

Award Number

CA-D*-FST-7105-H

Funding Agency

Center for Produce Safety

Investigator

Gary M. Smith, Ph.D.
University of California, Davis

Summary

Listeria monocytogenes is a food poisoning bacterium that can grow in the refrigerator or under other stressful conditions. To grow under stress, the organism accumulates protective molecules from the food in which it lives by the action of 3 transport enzymes. We will find what causes these enzymes to be synthesized and activated, and how they are activated. Our goal is to prevent infections. The ultimate impact is to reduce the viability of Listeria monocytogenes, particularly persistent strains, by understanding the mechanism of resistance to environmental stress and refrigeration. Reducing the viability will decrease the loss of life and economin burden of product recalls due to Listeria monocytogenes.